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Single-cell Sequencing of Thiomargarita Reveals Genomic Flexibility for Adaptation to Dynamic Redox Conditions
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The JGI announces FY25 awardees for our Community Science Program Annual Call
…   The JGI is excited to announce the 18 scientists selected for our 2025 Community Science Program Annual Call. These … will target sustainable energy solutions, focusing on lignocellulosic thermophiles and polymer degradation.  “We are … call, as well as our smaller-scale New Investigator and Functional Genomics calls, here on our website.   See below …
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JGI@25: From Life at the Extremes to Editing Genomes
Congratulations to Jennifer Doudna of the University of California (UC), Berkeley and Lawrence Berkeley National … scoutRNA Is Required for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: 10.1016/j.molcel.2020.06.022. Wright AV et al. A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR …
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Fungal Friends or Foes in Plant Roots
… health and diversity, which can in turn boost yields for both food and for candidate bioenergy feedstock crops. … plants (endophytes). These include genes that degrade plant cell walls and break down plant sugars. The results also … of the key community participants and enabling future metagenomics studies.   … The sequencing project was funded by …
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Crysten Blaby-Haas
… at Berkeley lab. She earned her PhD in Microbiology and Cell Science in 2011 from the University of Florida, working … joint user capability between the JGI and Molecular Foundry for genome-encoded biomaterial discovery, design, and … Hu F, Regulski M, Blaby IK, Ware D, Blaby-Haas CE. (2024) Functional diversification within the heme-binding …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes do, how they work, … PI on this project. “I view the program as an excellent platform to build collaborative research initiatives.” Yasuo …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… threads in the mix. But in the Petri dish, the thin vermicelli-like threads floating delicately above the leaf debris … National Laboratory (Berkeley Lab) and the Laboratory for Research in Complex Systems (LRC) in Menlo Park, Calif. … formation of pepins and how molecular processes within and outside of these structures occur and are regulated  also …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most … methods; shotgun metagenomic sequencing and single-cell sequencing. For years, extracting single cells and then …
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Workforce Development & Education Outreach
The JGI aims to inspire more students to enter the STEM workforce by fostering an understanding of our role in advancing the energy and environmental genomics research frontier.  Learn more about the JGI's … from high school to community college. … University of California, Merced … Alabama A&M University … CalTeach … Biotech …
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UC Merced Interns Reflect on Their JGI Summer Projects
… skills as well as build their network in the field of genomics and scientific research. The topics students worked … language processing techniques to categorize genetic information. Learn more about their work here in a series of … virtual events and technology enabled a fruitful experience for mentors and students alike. Tools like Slack, Google …
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Who We Are
… around 280 researchers and support staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB fosters team science and …
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Taking Stock of the Known and Unknown Microbial Space
… the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.  “We … said co-first author Dongying Wu, a member of the Functional Annotation team within the JGI’s Microbiome Data … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
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