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A Redesign for Yeast’s Genome, Chromosome by Chromosome
To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked … yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… single drop of water could outnumber a small city’s population, the number of viruses in the same drop—the vast majority … and genome size from small, to large and even giant. The genomes of giant viruses are on the order of 100 times the … which then helps the virus to replicate faster and produce more progeny. This can provide short- and long-term …
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JGI@25: The Little Alga That Could
In honor of the JGI's 25th anniversary in 2022, we have … and published in the journal Science . At the time, the project was co-led by Daniel Rokhsar, head of the JGI’s … impact. Her lab has sequenced four additional green algal genomes using Chlamy as a reference for functional …
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
On July 8, JGI’s DNA Synthesis Science group held a  JGI … looked at how different bioenergy relevant plants can produce species-specific blends of terpenoids, naturally … of the proposals. Upon approval from JGI reviewers, the DOE project managers review the proposals. The proposer of …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … A., Hadjithomas M., Varghese N. J., Paez-Espino D., Hungate project, collaborators Perry R., Henderson G., Creevey C. …
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Fungus Fuels Tree Growth
Researchers start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.   … Program in order to get  M. elongata and  I. europaea  genomes sequenced and annotated for this study. The team … 0002 01 to F. Martin), JGI Community sequencing program project (CSP570, DE-AC02-05CH11231), and National Science …
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Cultivating Symbiotic Antarctic Microbes
Nanohaloarchaeota cultures reveal they are symbionts and not free-living organisms. The Science Researchers … consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental samples and … (DP150100244) and the Australian Antarctic Science program (project 4031). The work conducted by the US Department of …
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DOE Metrics
FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal Actual Total* Actual % of Goal … counted once, even though an individual may have several projects/roles. Sequencing Quarter Total Bases (Trillions) … the interpretation of microbial, metagenomic, or plant genomes. [Download PDF] End-of-year Goal – Develop one new …
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How Filamentous Fungi Sense Food
… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … proposal akin to the Encyclopedia of DNA Elements (ENCODE) project, which is aimed at determining the activity, … enriching the work being done as part of the 1000 Fungal Genomes Project. Funding for the project was also provided …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
In honor of the JGI's 25th anniversary in 2022, we have … engagement activities under the umbrella of the SOD Blitz Project. In hopes of controlling the spread of the disease, … Science News of the Day: Stokstad E. Genetics. Genomes highlight plant pathogens’ powerful arsenal . …
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A Step Toward Controlling Soybean Rust
The United States  is the world’s leading soybean producer , and soybeans are used to produce biodiesel. The … Rust (ASR) and is the major pathogen of soybean. Left uncontrolled, soybean rust could reduce crop yields by as much … Program portfolio , Sebastien Duplessis of the French National Institute for Agricultural Research (INRA)  proposed …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial …
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