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Nigel Mouncey
… joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of … and Bioprocessing R&D Director and Leader at Dow AgroSciences in Indianapolis. During his time in industry, Dr. … responsibilities toward the JGI internal scientific programs, the affiliated DOE National Laboratories, the …
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Novel Viral DNA Polymerases From Metagenomes Suggest Genomic Sources of Strand-Displacing Biochemical Phenotypes
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iPHoP: A Matchmaker for Phages and their Hosts
… computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do … before, in all kinds of ecosystems. However, matching these viral genetic sequences to their hosts is crucial to … nutrient cycling, or carbon sequestration. Summary Existing programs use a variety of approaches to match a virus with a …
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Nikos Kyrpides
… for microbial genomes and metagenomes (IMG). He became the Metagenomics Program head in 2010 and has the combined … on Microbiome Research with an emphasis on Microbiome Data Science. His group is developing novel methods for enabling … the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . 39(5):578-585. Nayfach S, …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… process. The isotope labeling incubations can take hours to months, followed by weeks of tricky, laborious lab … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … this was the first workshop of its kind on SIP metagenomics,” Malmstrom said.  Increasingly, efforts like …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… revisited a number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental … a paper in the journal Science. It detailed how they’d used metagenomics — a then-novel approach which allows scientists …
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An Integrated Dataset to Understand Ecosystem Interaction
… between poplar trees and their microbial partners. The Science To help better understand how ecosystems work and … managed through human intervention. By leveraging metagenomics, scientists were able to analyze the DNA of … trees. The data set generated is 25 terabytes in size. Resources for genomic sequencing, analysis and characterization …
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User Executive Committee
… on JGI policies and practices that affect users and their science including technical capabilities offered, proposal …
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Philympics 2021: Prophage Predictions Perplex Programs
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Uncovering Novel Genomes from Earth’s Microbiomes
Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … Lab), and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of the microbial communities in … Path for Metagenomics Researchers Building upon these resources, KBase, a multi-institutional collaborative knowledge …
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JGI Mural
… genomics. Click on the images below to learn about the science depicted. The two-story JGI mural was commissioned …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms … interactions. This work,  recently published in  The ISME Journal , by contrast, relied on methods that eschew … the virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for …
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