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Natural Prodcast Episode 21: Elizabeth Parkinson
… like a lot of people hedge their way into natural products by starting out in synthesis and then discovering more-- … So chemicals are their way of talking. You bring up an excellent point though, and I think this is an area that is a … in is actually seeing whether we could go into the genomes and predict what the natural product might actually …
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Synthesis
… convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for … to validate hypotheses generated from mining genomic data by designing and assembling physical DNA constructs that can … a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods … …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal … and developed new tools to map that soil RNA to fungal genomes.  The U.S. Department of Energy (DOE) Joint Genome … functions across different forests. Primary metabolism, cell activity, and fungal development looked quite alike for …
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From Competition to Cooperation
… lifestyles across multiple fungal lineages. The Science By comparing 135 fungal sequenced genomes, researchers were able to carry out a broader … saprotrophs in the forest. White rot can break down the cellulose, hemicellulose, and lignin in plant cell walls, …
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Webinars on Offerings & Capabilities
… webinars that can help you through the submission process by better understanding the capabilities and resources …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… genetic differences and then expanded on on that knowledge by doing a second postdoc with Yi Tang at UCLA and then kind … organisms we’re finding– at least by looking at their full genomes — are really not like anything that’s been … , but they’re new species. And they have very similar [genomes] to other Streptomyces , for example. So there’s …
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Characterizing Communities: JGI Announces Latest CSP Portfolio
Proposals aim to sequence and annotate genomes from Antarctica to Africa to global oceans. Through … Additionally, 40 percent of the proposals were submitted by researchers who had not been a primary investigator on … our efforts to characterize poorly-studied algal and viral genomes, and integrate with key DOE Office of Biological and …
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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both … August 26, 2021, in Nature Communications , researchers led by Hal Alper at The University of Texas at Austin and …
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Natural Prodcast Episode 8: Eric Schmidt
… hard it was – it felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to … way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a ribosome. Then, some … with each other. There’s a lot of leading data from excellent groups about specific interaction motifs. But …
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Refining the Process of Identifying Algae Biotechnology Candidates
… [subhed -- copy to summary above^ as well ] The Science The recipe for growing algae as a source of sustainable biofuels … cook knows, recipes can be refined for best results, often by starting with identifying the right ingredients. … Labs to screen, characterize, sequence and then analyze the genomes and multi-omics datasets for algae that can be used …
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Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
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A compendium of bacterial and archaeal single-cell amplified genomes from oxygen deficient marine waters
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