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… there. This is Dan again, and you’re about to listen to the 3rd and final part of Natural Prodcast’s “Primer” episodes. … I hope you’ll stick around. But, for now, here’s episode 3 of the Primer! — DAN: So, you know, in the in the 50s 60s … your cultures, but then you’re going to find another 20 or 30 secondary metabolism pathways that you didn’t even know …
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… that I was exchanging with people. So I think I wrote 3,000 emails in the course of one and a half year while … some people went as far as saying, OK, we’re going to take 300 strains from our labs and measure them on their mass …
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… with us? Brad: Unfortunately, not. We lost him about 13 years ago. So, I wish he was still with us because I know …
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… they had the same conserved polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: … anybody in natural product discovery in any field and even 30 years ago would say it’s the [key to] success. And that … at Scripps, I guess, 22 years ago. And it’s over 130 steps to make everninomicin. DAN UDWARY: Yeah, one of …
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… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … as much about it as possible starting with we picked 183 of them. And we sent that list to the Joint Genome … an unusual acyl-homoserine lactone signal . mBio. 2023 Aug 31;14(4):e0101023. doi: 10.1128/mbio.01010-23. Publication: …
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