Search

… of soil-sediment environments, water and air-atmosphere with the humans and the biosphere), including the global carbon cycle. The JGI is sequencing large numbers of microbes and microbial … genome sizes and their cells were not observed to associate with host cells. In the  Proceedings of the National Academy …

… value to the other commonly used culture-independent sequencing approaches including amplicon and metagenomic sequencing. For example, they showed that the composition of … cells harbored mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that …

… of Energy.   The JGI provides integrated high-throughput sequencing, DNA design and synthesis, metabolomics and … created in 1997 to unite the expertise and resources in DNA sequencing, informatics, and technology development … Integrative Genomics Building (IGB), a home it shares with the staff of the DOE Systems Biology Knowledgebase …

… candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great Plate-Count … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary … of interest, prior to and in conjunction with whole genome sequencing. … Jean-Marie Volland: Assistant Professor, UC …

… to improve genome recovery from single cells and to build sequencing libraries from minimal DNA input without amplification. …

… genomes and directly link functional information with individual cells. Research Team    … The JGI uniquely … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity … and sequence microbial aggregates after first imaging with various microscopy techniques … Stable isotope probing …

… for multiple applications.       Despite advances in sequencing technologies and computational methods in the … of the microbial communities in the environmental samples without needing to isolate individual organisms, using various methods for processing, sequencing and analysis. “Using a technique called …

… pipeline. He also explores new methods for creating sequencing libraries and optimizing various processes. …