Search

Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, … , 2022 Ke et al., CRISPR-CRAGE enables rapid activation of secondary metabolite biosynthetic gene clusters in bacteria, …

… — making it difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, … to protect themselves from environmental stresses, ferns’ secondary metabolites and associated genes are great resources for …

… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach to better understand … “So, that diversity is definitely holding a lot of new secrets in terms of functional diversity as well.”  …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … Successful applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be … such as DNA-SIP, Protein SIP, Flux Balance analysis with metabolites, Isotope Ratio Mass Spectrometry, NanoSIMS, and …

A preview of how large-scale single cell genomics complements … studies. The Science Researchers demonstrated the value of conducting large-scale single cell genomics by collecting … Such techniques take advantage of bioinformatics tools for  extracting snippets of microbial genomes directly from …

… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … sequencing and single-cell sequencing. For years, extracting single cells and then amplifying their DNA for …

… efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … techniques, the platform delivers rich metabolite profiles from diverse biological and environmental samples in support of user science.  Capabilities offered by the platform are a …

The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … with results published in the  November 2022 issue of Microbiome . High-throughput stable isotope probing (SIP) … up the pace at which researchers can extract the bioenergy secrets they hold. HT-SIP is a capability available to …