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… in the old days, saw how hard it was – it felt kind of like training for a marathon by running at a high altitude! … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the … and efforts to refactor entire chromosomes, such as a yeast chromosome project. These advancements contribute to … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of …

… can I make that big, beautiful molecule? And so I’d like to think I’ve evolved a bit since that time. And I … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

…   The Joint Genome Institute's Biodesign Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … Check out our organism-agnostic CRISPR gRNA design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… Nadine Ziemert from the University of Tübingen in Germany. Like me, she’s a genome miner and has been involved with the … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… As a National User Facility, the JGI serves more than 2,500 users … National Labs and industry, including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, … Our User Programs entail a competitive, proposal-based process including peer …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … him. And I said, you know, I’m here to find a job. I would like to do something completely new. And that is to begin to … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… from the Great Salt Lake, and you’re going to learn, like me, what a “haboob” is. Then, we switch interview … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… or reaching out on Twitter to @JGI or me @danudwary. Like I said in the intro to the first episode , after this … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and … 1) Complete Sample Metadata form Sample metadata is collected via …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at Lawrence Berkeley National … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a high-throughput AI-centric genomic science user facility …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs …