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… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also … offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal analytical … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… by the Biological and Environmental Research program, the Joint Genome Institute provides advanced genomic capabilities, … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … basis of their behavior in the environment.  The JGI genome sequences and metabolomes of microbes and microbial …

The mission of the Joint Genome Institute is to serve the scientific community as … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … Patrick would spend time between our two laboratories doing metagenomics, some genomics. We were a little concerned …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … a mixture of, for example, metatranscriptome sequencing, metagenomics, single cell genomics. We even do the flow … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… on DNA sequencing and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… to onboard users and guide them through the process of working with our facility. This includes help with: preparing a Statement of Work, … Natasha Brown Supply Chain Manager Tijana Glavina del Rio Metagenomics         Danielle Graham Microbial Program Nancy …