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… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … in depth. So some of these that were initially identified by Russell Cox, like [INAUDIBLE]– DAN UDWARY: Explain to my …

… next review cycle. All proposals undergo technical review by JGI staff as well as staff at the other participating … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to … panel of bacteria and see what happens. Is that– what’s the modern way of doing that or is it still the same kind of …

… of Energy Office of Science user facility supported by the Biological and Environmental Research program, the … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … must clearly demonstrate relevance and translatability to freshwater, coastal or terrestrial systems. Additional …

… this episode we’re going to finish up by talking about the modern, post-golden age history of natural products … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … execute a 2024 version .  The recent updates were approved by the DOE to address the DNA Synthesis program. When fully … to a new commercial institution requires approval by all parties. … After your proposal is approved, the …

Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … text matching machine learning model does better with more modern articles than it does with older articles. Some of … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… medicines and medicinal plants with the pursuit of modern drug discovery. It’s also the kind of book we can … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … requirement, for culturing, and then of course using modern phylogenetic tools measuring genes, the 16S gene, and … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … to do natural products chemistry. I get asked a lot about modern or mixed approaches, and we use a lot of those in my …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … negotiation with the JGI.  Investigators with grants funded by DOE-BER requiring support from the JGI may  submit … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation …

Data produced and released by the US Department of Energy (DOE) Joint Genome Institute … protection of certain types of data to support their use by those generating data. The JGI Data Policy applies to … embargo starting at construct or strain delivery.  Detailed sequence information for constructs are made publicly …