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Cooperative Biodiversity Groups, and it’s this great program funded by the National Institutes of Health … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

But most people that know me call me Kate. Dan Udwary: Great. So we’ve got Kate here today, and we wanted to talk … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… one of the best things that we do is work with this really great group of biologists that know what they’re doing much … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … Two fanatic PhD students. Alison Takemura: It sounds great. Yeah, it sounds like it was really needed at that …

… sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs … in length, cloned into vector of choice Glycerol stock of sequence verified clone 170/NA DNA Synthesis Constructs …

… working on it because I really do want you all to hear this great conversation with Aaron Puri. He is an Assistant … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… after listening to this, you think you actually do have a great project that would awesome for a CSP, or if you’re a … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… the JGI. The quality of the starting material is one of the greatest predictors of a successful sequencing project. It … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… as well as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified using …

… of mine. I met him when we worked together at the late great Warp Drive Bio, a biotech startup where we did genome … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… the world. … But, meanwhile, I’ve been sitting on all these great interviews recorded a few months ago at the SIMB … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …