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… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … in our bedroom together with us still while she’s still four months old. So it’s not a bad location for a little … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … They produce a large array of different molecular species related– chemically related– but nevertheless we did … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less … they were expecting to. So you might know of like three or four or five molecules that you maybe had found and ground …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … then we would take our two foot core. And so that’s only four feet in. And there is quite a bit of sun and exposure … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … tool for generating synthetic sequencing data from genomic sequences … A predictive tool for microbial symbionts in environmental sequence data, including microbial phenotype along the …

… our User Program’s Community Science Program, the JGI sequenced and characterized 270 genomes of the Clostridium … To meet these needs, the JGI deploys state-of-the-art sequencers and platforms dedicated to DNA synthesis, …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … from certain kinds of environments or certain kinds of species or whatever. So for example, if you wanted to go …

… food and health and botanical medicine. I’m also a mom of four kids now so ranging from 8 to 17 in age, so my home … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

… through isolation and genome sequencing of new fungal species.  Students collect fungi, sterilize tissue, isolate … and distribution of fungal genome datasets. It includes JGI-sequenced and publicly available datasets encompassing a … and researchers, facilitating the transition from genomic sequences to biological inference and understanding of …

… For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we …