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… schedule for a while. Moving forward, I’m hoping to get a new one out every two weeks. This time, we’ve got a great … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly … genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural …

… of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission … technical help, feedback or a guided walk-through of the new Data Portal.  … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic …

… and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop … the program strives to facilitate the discovery of new bio-based molecules that can drive innovations in … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

… Right. Kate Duncan: And Pseudonocardia . And we’ve got new species which we’re currently in the process of almost … there have been huge advances in both. The cool thing about genomes is you can, well, if your assembly is good, you can … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is …

… including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… this an awfully long time ago, and she’s been in her new job for a long time now, but I guess you all might not … powerful people. These were people that really controlled microbial drug discovery. And a guy like me, with no … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … systems can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   …

… Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize microfluidics/microdroplet … technology in order to enhance the quality of single-cell genomes and directly link functional information with …

… read all 400 pages of her life and I feel like I have a new friend that I’m really eager to talk to. So our guest … it’s not that easy. There are still not that many plant genomes, certainly nowhere close to bacterial kinds of … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… example of probing fungi for natural products and finding new things. And so, really happy to have you here. And … of the food was bad from mold, but that’s all I really knew. I didn’t really think about it a lot. And so after I …   DAN: Got it.    NANCY: And this is really to complete the genomes, and I’m really thankful for this. It sort of goes …

… that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the … and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … IMG kind of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial …

… by what’s called “find and grind”. So you would find some new source that you hadn’t explored before. Like, you know, … C, and you’ve got a new molecule, right? And so if you have 1000 A’s and 1000 B’s and 1000 C’s, then if you’ve got a … we can find more things. Turns out some of the early genomes that were sequenced for, say, Streptomyces – they …