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Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … nature does this with such elegance And also to take advantage of the biological properties that these molecules have … I was a graduate student doing total synthesis where our gold standard was, if you’re doing three reactions a day, …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is still … that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … essential for fundamental growth, provide critical advantages to the organisms producing them, and are often involved … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … is 1,000, 2,000, 3,000 meters below sea level. And we’ve managed to culture, and in the lab, some rare actinomycetes. So … Right. Kate Duncan: And Pseudonocardia . And we’ve got new species which we’re currently in the process of almost …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … which might lead you to changes in bioactivity, and new uses for these peptides in medicine or materials science … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … solutions in energy, agriculture and ecosystem management. … The Microbial Program focuses on using advanced … with over 15 million viral genomes and fragments. … GOLD is a web resource for comprehensive access to …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … if we’re finding an audience outside of just us. If you’re new to natural products science, please let me know! I’m … the idea that you could go internationally to do the next stage of your training and that there might be more to be …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … genomes, SAGs, MAGs, metagenomes and metatranscriptomes. … GOLD is a web resource for comprehensive access to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … marine natural product biosynthesis and at the beginning stages of connecting molecules and genes. And then genomics … pretty much goes on. We’re looking at, now, diatoms and golden algae, and, so, really trying to challenge ourselves …

… know that that’s ever necessarily like a good description of anyone because chemistry means a lot, especially when … people were using for medicines in this very remote village. And so it was done, like as soon as I did that, I was … in how the community itself works together to elicit new metabolite production. And we are also interested in how …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … I worked on a team at the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept … got really high GC content, which means their base usage is skewed, and that can mess with some of the technology …