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… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … which has really shaped some of my views and language, and I hope you’ll enjoy it too. So here we go– episode … chelate any divalent metal. So it could be iron, could be silver, it could be copper, but unless you don’t mess about …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … this an awfully long time ago, and she’s been in her new job for a long time now, but I guess you all might not … we want to talk a little bit about. It’s sort of early stages. But I think that is emblematic of some of the research …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … is 1,000, 2,000, 3,000 meters below sea level. And we’ve managed to culture, and in the lab, some rare actinomycetes. So … Right. Kate Duncan: And Pseudonocardia . And we’ve got new species which we’re currently in the process of almost …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … if we’re finding an audience outside of just us. If you’re new to natural products science, please let me know! I’m … the idea that you could go internationally to do the next stage of your training and that there might be more to be …

… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is still … that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the …

… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … essential for fundamental growth, provide critical advantages to the organisms producing them, and are often involved … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop …

… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to all …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … which might lead you to changes in bioactivity, and new uses for these peptides in medicine or materials science … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … maybe obvious or notable. We are still in – not an early stage. I think we can identify most secondary metabolism … try to find more molecules like this. It became sort of a “golden age” of drug discovery, antibiotic discovery.  DAN: …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal … solutions in energy, agriculture and ecosystem management. …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to … The Metagenome Program focuses on the high-throughput sequencing of …