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… the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … know, do your organic reaction and see if it smells like a pine tree. Like there’s no cookie cutter reactions here, …

PI and receive permission for their planned work.   … For sequencing or metabolomics projects: data are subject to a  … Policy … Data Management at the JGI … Policy Definitions … Sequencing and Metabolomics projects … DNA synthesis …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in … … The Metagenome Program focuses on the high-throughput sequencing of microbial communities to uncover the complex … of phylogenomic novelty: Advances in metagenomic sequencing, assembly and binning have enabled reconstruction …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … it was a big deal. And you really had– I mean, the whole sequencing endeavor, had a cost, how much blood, sweat, and …

… environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … … The Fungal & Algal Program harnesses cutting-edge sequencing technologies and advanced genomic analysis to … and biogeochemistry. The program’s focus is on large-scale sequencing efforts that survey the vast phylogenetic and …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … the JGI. And so now here at the JGI, I work with all of the sequencing data that the JGI produces to try to find and …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore … … The Microbial Program focuses on using advanced sequencing technologies to explore microbial diversity — … datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in …

Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … facility, evolved, and as we started to do more than just sequencing, we thought the name community sequencing program … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … that I never anticipated starting– that’s not why I came to the University of Utah– is looking at the … to grow. If you hear Nigel talk, he is very interested in sequencing a lot more natural product-heavy culture …

… plan is written into a Statement of Work document. … For sequencing projects, once work is under way, raw sequence … in publication of results. … Submission … More on Sequencing Projects …

… biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … gene clusters. And I had heard the first rumors of people sequencing like these enormous numbers of genomes, like 20 … families across all genomes. And the acceleration of genome sequencing, especially in bacteria, has been enormous. There …

For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … with DOE mission-relevant projects that call for expansive sequencing, synthetic biology and metabolomics capabilities … Letters of Intent. Proposals may include synthetic biology, sequencing and metabolomics. Proposals may include synthetic …