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New Lineages of Life Group
… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research … The ISME Journal. 8 (8), 1634-1644 … Publications … For further details, please reach out to the Group Lead …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility … staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB fosters team science and … as the DOE Systems Biology Knowledgebase and the National Microbiome Data Collective.        … Learn more about our …
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A unified catalog of 204,938 reference genomes from the human gut microbiome
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Data Ecosystem
To expand access to integrated data, improve tools and infrastructure as well as … to both expertise and infrastructure to facilitate these efforts. Particular areas of emphasis will be the development of tools and infrastructure for microbiome data science, and the development of new …
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A genomic catalog of Earth’s microbiomes
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Micro-Scale Applications Group
… of single-cell genomes and directly link functional information with individual cells. Research Team    … The JGI … analytical standards to accurately measure environmental microbiome activity levels.This functional assay lets us move beyond cataloging the genes of microorganisms and start making …
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Natural Prodcast Episode 23: Aaron Puri
… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the afternoon of the day I’m due to release it, … or methanol, and now we have access to the whole sigma catalog of precursors in their 12C form. You can feed those …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
In honor of the JGI's 25th anniversary in 2022, we have … challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen … the ability to break down hardy plant cell walls and therefore hold clues to how humans could do the same on an …
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Natural Prodcast Episode 7: Ben Shen
… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a perfect storm in … delivery mechanism. So, the polymer structure has specific preferences to cancer cell lines. So, that was introduced in …
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Uncovering Novel Genomes from Earth’s Microbiomes
… leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications.   … . Known as the GEM (Genomes from Earth’s Microbiomes) catalog, this work results from a collaboration involving … he’s interested in expanding the diversity of the reference database he’s developing called the  Microbial …
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Natural Prodcast Episode 4: Nancy Keller
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting some conversations … they deserve. They are so exciting. I get frustrated. Like microbiomes  – you know how that’s a big deal now. You go to …
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Natural Prodcast Episode 11: Marnix Medema
… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … similarity to a gene cluster with a known compound from the reference database: It must be identical. It must be that … we, for example, are really interested in metagenomes and microbiomes and figuring out which gene clusters are …
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