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… to predict or just understand better the language of microbial cell-cell communication. And he told us about his … the future. So, then we were using these probes to look at host pathogen interactions mostly with like enteric … what signal is being made. And so we picked a bunch of very diverse ones to try to learn as much about it as possible …

… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to assess microbial activity across ecosystems.  By studying microbial …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the biological … that enable fungi and algae to play a vital role in carbon cycling, biodegradation and biogeochemistry. This research …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties … ecosystem function.  The Environmental Genomics group also hosts the Viral Genomics group . Research Team    …

… for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … challenges in the sourcing, recovery, and utilization of critical minerals and materials. The proposal submission … Access to the Molecular Foundry and use of JGI capabilities is free. The JGI supports remote users. …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … advances in management, processing and visualization of “big data,” and artificial Intelligent/machine learning … breakthrough discoveries and catalyzing a major transition of biology into data science.  Research in the Kyrpides …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of biofuels, biochemicals and other bioenergy solutions.  … project. These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … to the end. It’s not only the final product that is highly diverse, but also many of the intermediaries. And, in a way, … the producing organism and strong interactions and the host or even in tripartite systems. So, in those cases, it’s …

… Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … at the end to get the compound expressed in a heterologous host strain. DAN UDWARY: Yeah, sure. That’s very similar to … But we also have, in collaboration with other people, lake sediments. We have microbiomes from different organisms, …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and … Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of the product and … assembly from virus pools/plaques obtained from a single host, many unordered contigs. Assembly, annotation ( IMG ) …

… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … their potential applications in the bioeconomy including biofuels, biochemicals and sustainable agriculture. …