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The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis … Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … to determine coverage of variants depends on project Fungal Minimal Draft Lower coverage short-read whole genome …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to … natural products of microbial origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, … where this happened have a tendency to be susceptible to a fungal infection of rye grain – a specific fungus, Claviceps … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that …

Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way … PI and receive permission for their planned work.   … For sequencing or metabolomics projects: data are subject to a  …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … associated with the chemistry department as well as the life sciences department. So welcome, Alison to today’s … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … of all publicly available genomes from three domains of life, in a uniquely integrated context.  … The IMG/VR system …

Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … material is one of the greatest predictors of a successful sequencing project. It is imperative that users properly …

FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 …     Q4 2025 175     2,167     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … Novel approaches are being explored to predict microbial lifestyles using AI-driven analysis of such datasets. The …

… where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans … took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  DAN:  And … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… things, because a lot of what we do at JGI in terms of the sequencing that we do is very people-disconnected, and … could be used to treat these highly resistant bacterial and fungal pathogens. And we’ve actually just wrapped up a year, … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …

… at some topic that I’m working with about now. I made a tree of different compounds, and I’d looked at it from an … I think. DAN UDWARY: Yeah, and that was a JGI Community Sequencing Project. You’re right, yeah. NADINE ZIEMERT: Yes. … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …