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The Metagenome Program uses advanced sequencing technologies to … microbial and viral activity, transcription regulation, and noncoding RNAs in microbiomes. The insights from this work … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

The focus of this group, in recent years, has been to bring … expression and functional exploration.  The developed strains represent an additional phase of user-accessible project types, in which DNA-based molecules can be chromosomally …

Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing to enable biological … The team works hand in hand with the Project Management Office to help ensure the JGI’s genomic capabilities are …

Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … about the project and he arranged funding to do it nonetheless from his own group’s funds. So I could start …

And it actually was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that … of genes. It was actually originally predicted to be a nonribosomal peptide synthetase but then flanked by these … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … the DOE's vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and …

The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … The  1000 Fungal Genomes Project is a five-year project to sequence 1000 fungal genomes from across the Fungal Tree of …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … 10 Tbp sequencing, 500 kbp synthesis, and 200 polar/500 nonpolar metabolomics samples, and should generally conform … science.  Projects include de novo generation of genome data, assistance in interpreting and/or building on …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … and you can really see there is a gene cluster, or there’s none anymore. So this evolution of really when you don’t … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural … the same medium from the previous experiment, and you get non reproducible results, or chemical diversity. I mean, … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

Below is a brief description of the process needed to prepare and ship samples for … Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your organisms? … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …