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… interactions, over ecological and evolutionary time scales.The Metagenome Program combines large-scale, time-series metagenomic data with detailed … the research community to perform large-scale multi-omics analyses on new and existing microbiome data.   … The IMG/M …

… sophisticated tools, because now we had a very reasonably large set of articles which had been manually curated for … trade with the collaborators. So, we used those initial analyses we’d done by hand, in order to build a machine … is likely to be in the environment? Can we use this broad-scale view of the chemistry in order to start to make …

JGI Mission As a U.S. Department of Energy Office of Science user facility supported by the … Genome Institute provides advanced genomic capabilities, large-scale data and professional expertise to support the global …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … bioeconomy applications. The program provides high-quality, large-scale genomic data to advance microbial research that drives …

… .” This is kind of like a CSP, but you would be proposing a larger project that requires the work of two or more DOE … a new investigator who wants to try out something smaller scale, or if you’re just curious to know more, then I really … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

… and rate and drive down the cost of producing riboflavin at scale.  DAN: Got it.  NIGEL MOUNCEY: And I did that for … worked for the best part of 20 years on products that were largely in commercialization, I thought it’d be great to … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for the … them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The … the deployment of computational workflows at peta- and exa- scales on multicore and many core architectures with the …

And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … assays is what those would be. The work that we do at larger scale in order to look at the chemistry a little bit more …

… or the genes that could encode for that right next to a larger biosynthetic gene cluster the products of the … has been fun because then we’ve been able to blow out the scale a little bit for the project. DAN: Do you see broader … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … they were known as the most toxic molecules, and that human beings know, today, for small molecules. So they’re in the picomolar range. ALISON: …

… enable the exploration and identification of small and large structural variation — this variation drives major … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of … produces high-quality de novo assemblies for very large-scale single genomes, based on the JGI assembly tool …