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… sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  … will develop fuels and products by integrating three highly interconnected DOE priority areas of Feedstock … to develop valuable byproducts from lignin left over after biomass processing. Great Lakes Bioenergy Research Center , …

… of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … collection and storage (from PacBio) Best practices for High Molecular Weight DNA extraction and quality control …

… first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism … gap. A primary goal is to get  insights into the coding potential of candidate phyla  to decipher their possible … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

… and resources. Our vision is to lead genomic innovation for a sustainable bioeconomy. ALL PROPOSALS must support the … U.S. Department of Energy.   The JGI provides integrated high-throughput sequencing, DNA design and synthesis, … strains, or enzymes to convert plant biomass components into fuels, chemicals, and bioproducts, …

… overview and major challenges of host prediction methods for uncultivated phages.  Current Opinion in Virology .  49 … Biotech .  37 , 29–37 Roux S, et al. (2016) Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … ones? And which groups or families of gene clusters are potentially novel. So it might yield novel pathways of …

… mining and the directions it might take in the future. I highly recommend it. I’ll link to it in the show notes. … that example, was it the case where that colleague saw a potential mechanism for why there would be this … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my work, in … And you want to have good binding to your substrate and high turnovers. But if you have those things, can you also …

… a science-y kid? JACLYN WINTER: I was not actually. So in high school, I didn’t– well, I guess– I mean, a few people I … the University of Utah– is looking at the natural product potential of microorganisms from Great Salt Lake, which is a … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … chemistry that deals with reactive oxygen species and so potentially could go down that route.  DAN: So the sun … metabolism you know those numbers are still actually pretty high in terms of understanding from just sequence gazing …

… more about Tiny Earth and the JGI’s role in the project by watching Amanda Hurley’s presentation from the 2019 JGI … Marc was the Head of Experimental Genomics there, before he decided to leave for graduate school and pursue his … at, historically, for these pathways, they’ve got really high GC content, which means their base usage is skewed, and …