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… Biological systems hold extraordinary potential to power innovation in energy, materials, and … and AI-driven analyses that convert biological information into actionable insights and solutions. … pathways for producing biofuels, biochemicals, and other high-value bioproducts. Critical Minerals and Materials …

… of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … quantity and quality has been the rate-limiting step for many projects at the JGI. The quality of the starting … collection and storage (from PacBio) Best practices for High Molecular Weight DNA extraction and quality control …

… the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying … to environmental changes. The program lays the groundwork for sustainable solutions to current problems facing …

… sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  … in the BER funding call, proposals are NOT eligible for BERSS support through the JGI (with the exceptions of … negotiation with the JGI.  Investigators with grants funded by DOE-BER requiring support from the JGI may  submit …

… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … The “Great Plate-Count Anomaly” first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism … the metabolic potential of uncultivated lineages is of high value to establish models and hypotheses, experimental …

… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts … including especially metatranscriptomics, to better highlight and ultimately predict the main viral impacts in …

… mining and the directions it might take in the future. I highly recommend it. I’ll link to it in the show notes. … that example, was it the case where that colleague saw a potential mechanism for why there would be this … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … ones? And which groups or families of gene clusters are potentially novel. So it might yield novel pathways of …

… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my work, in … And you want to have good binding to your substrate and high turnovers. But if you have those things, can you also …

… a science-y kid? JACLYN WINTER: I was not actually. So in high school, I didn’t– well, I guess– I mean, a few people I … the University of Utah– is looking at the natural product potential of microorganisms from Great Salt Lake, which is a … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… more about Tiny Earth and the JGI’s role in the project by watching Amanda Hurley’s presentation from the 2019 JGI … Marc was the Head of Experimental Genomics there, before he decided to leave for graduate school and pursue his … at, historically, for these pathways, they’ve got really high GC content, which means their base usage is skewed, and …