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… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … their potential applications in the bioeconomy including biofuels, biochemicals and sustainable agriculture. …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … to identify new divergent lineages and expand the Tree of Life. We then investigate the coding potential to find … complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient cycling and bioproduct … automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … where those sequences are, and then you can know what those regulators are regulating. BETSY PARKINSON: Exactly, yeah. …

… Outreach at JGI takes many forms: We offer internship opportunities through working directly with … Overall, our aim is to inspire students and established professionals to explore opportunities in STEM by providing … learning opportunities and ultimately, an understanding of the JGI’s role in enabling complex biological and …

… A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, seen in a … The Impact Shrub willow and its close relative  Populus trichocarpa,  or the poplar tree, are potential biofuel … This work was supported by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to …

… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … soils compared to the conducive soils? So which ones are enriched in the soils that are suppressive? And then also when …

… After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was … tissue-specific in fungi. Some might go be produced in a sexual spore, some might be in an asexual spore, some might … to a compound that, with the exception of maybe the trichothecenes, does nothing to the plant? Maybe it actually …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … products is that we don’t know what all the biosynthetic gene clusters look like.  DAN: For sure.  MARCY: We have so … of environments that we’ve looked at, like the nutrient rich tropical kinds of environments, where there are more …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied …

… It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … then we much to our chagrin found that they had the same conserved polyketide synthase and then P3. We still don’t … have been actinomycete-specific approaches. And you can enrich for rare actinomycetes by doing some tricks. Treating …

… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … along with their associated viruses and mobile genetic elements. Beyond exploring and characterizing … drive innovations that could advance our understanding of Earth’s ecosystems. …