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… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … were looking at these genomes for the first time getting excited about this. And so you find these clusters. And one … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the Peace Corps is there was a visiting professor from Penn State. In this seminar this guy was talking about this … give you something that’s quite different with enhanced properties. So you still have to decide carefully which …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … natural product gene clusters, and we’re all really excited about that, and I think that comes across in the … a collection of half of the bigger pharma in the United States. It goes way back, including Wyeth, Millennium, and …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … PARKINSON: Awesome. Thank you so much for having me. Really excited to be here. DAN: Happy to have you do it. So, I … and making derivatives of this to test its anticancer agent properties. And on the one hand, it was really great …

… about definitions around words I made a possibly false statement. I said that I thought that the terms secondary … by two authors called Firn and Jones. I’m sure that people excited in natural product biosynthesis overall have had … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … this conversation about why the ocean was basically unexplored until the 70s, and how diving was the catalyst of that. … TAKEMURA: Hey, Dan. DAN UDWARY: So Alison, I’m really excited today. We have, by far, I think, one of the most …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … families. And he tells us about forthcoming efforts in paired-omics data sets and seeking to interpret function from … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … sound like that was initially something that you were excited about doing? NADINE ZIEMERT: Now, that’s all I do … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … interactions. Novel approaches are being explored to predict microbial lifestyles using AI-driven analysis … and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our understanding …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … products discovery, and we’ll talk a lot about the current state of things, and what we’re hoping to accomplish at JGI … diversity that we have at our fingertips. So I’m very excited to learn more and hear more about what JGI and …

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