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… program supports cutting-edge research in synthetic biology by synthesizing genes, pathways, and whole chromosomes for … and bioproducts. Efforts include developing innovative screening technologies and computational tools that enhance … the DOE's vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and …

… data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The … fraction, AF) have been computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes based on their pairwise AF and ANI …

And it actually was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that … cluster with me because it turns out that oftentimes in bacterial genomes if you have a quorum sensing system or the … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… of Energy Office of Science user facility supported by the Biological and Environmental Research program, the Joint Genome Institute provides advanced genomic capabilities, … National Antarctic Museum (MNA-CCFEE). … The JGI was created in 1997 to unite the expertise and resources in DNA …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural … BARONA-GOMEZ: Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … research in and around drug discovery, which includes screening methods, genome mining in cave microbiomes, and … just– and then in terms of there’s sequencing an organism by shotgun, which is what we did, we didn’t even sequence …

… works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the molecular … state-of-the-art instrumentation and informatic approaches.By bridging genomics with metabolomics, the Metabolomics …

Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … home. Or actually not my room, it’s the room of my little baby daughter, who inherited this room from her sister. And it … Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And so yeah, we use antiSMASH to identify …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … search away! If you like these primer episodes, let me know by emailing us to [email protected], or on twitter @JGI or … ALISON: Hmm. It kind of – it’s kind of like I’m smelling bacterial perfume. I mean – but it’s purposeful so it’s some …

… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … like a lot of people hedge their way into natural products by starting out in synthesis and then discovering more-- …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … hard it was – it felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …