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… what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … primer episode, we talked about genome mining through some metagenome associated genomes. And yes, antiSMASH is … the action of the microbiome because if you sterilize the soil, the protective effect is gone. You can transplant the …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … off through these areas. And you can do– with a teaspoon of soil from outside, you maybe have to do a 10,000-fold … just now switching from intermicrobial interactions, studying intermicrobial interactions by imaging interactions …

… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … the first place? ROGER:  So I was originally trained in the UK, I did my undergraduate degree at University of Leeds. … natural products science as a field, we have arguably been studying microbial natural products in an ordered way for …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … are many others, including Streptomycetes, which are common soil bacteria. DAN UDWARY: Yeah, we talk about them a lot …

… expertise to support the global research community in studies of complex biological and environmental systems. … our service to the community through responsibly managing our people and resources. Our vision is to lead AI-driven genomic innovation to advance biotechnology.   …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new … that utilize microfluidics/microdroplet technology in order to enhance the quality of single-cell genomes and … uniquely offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  … crack this case, then that would open up our field to other study. And so it was kind of an early example, to try to …

… in Florida to discuss a JGI pilot project involving soil sampling in the Florida Everglades to help train the … Jonathan’s email request reached  Emiley Eloe-Fadrosh , the Metagenome Program Head at the  U.S. Department of Energy … do an environmental microbial community (metagenomic) soil study in an untouched region of the Everglades, the …

… and postdoc at Lawrence Livermore National Laboratory, is using bioinformatics and isotopes to track how viruses influence the flow of carbon in permafrost.  …

… DAN: You’re listening to the US. .Department of Energy Joint Genome … for antibiotics and the microbes that make them is in the soil. There’s … uh… there’s an issue there though, in that … get produced changes in response to different selective pressures. It’s really hard to assay because oftentimes we …

… Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. How are you?  MARCY: Am fine. I live in a … now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … Marcy. So I was wondering, how did you get interested in studying natural products?  MARCY: That is a great question …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics Below is a … metabolites and unidentified features in spectra. 167/214 Metagenome Metatranscriptome Environmental transcript …