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… convince those people of that fact, however, a long time, 10 years! ALISON TAKEMURA: Wow. It’s all happened so fast. I … of the molecules in ecology. And that took another 10 years at least. But I had several students. And I worked … cancer. And that means that you have to provide up to maybe 100 grams of the natural product. And that was, for us, very …

… so there are– I hesitate to make a guess but maybe 50 to 100 different strains and they are in individual tubules.  … in the field, these glacial bacteria grow slow and it’s not 100% clear that we know what their biological activities … call this the needle in the Haystack. Because if we have 10,000 features which one do we look at because we are a …

… pairs. It was not linear, like Streptomyces , but circular. 10% of the genome encoded natural product pathways. Dan: … Brad: Yeah, at that time, that was new, right? Like, my god 10% of the genome makes small molecules that have, you know, … of changed over the years. And I think maybe over the last 10 years, I’ve really become a fan of having postdocs, and …

… people what that number is. BETSY PARKINSON: So micromolar, 10 to the negative 6th. Nanomolar, 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY …

… tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … is really happening, if people are really going to sequence 10 or 20 genomes at once then we really need to have … heard about biosynthetic gene clusters and it’s one of the 10 analysis that you do, then it’s very easy to think that, …

… proposals as well. I’ve been at the JGI for 20 years, and 10 of those years, I’ve been a project manager. MENAKA … amount that they can request. So the minimum request is 100 kb. The maximum request is 500 kb. DAN UDWARY: For DNA … chance of getting approved because you requested only 100 kb versus 500 kb. In the lab, they’re going to do the …