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… out to many researchers with the hope of getting support for a research project for his class of 18 juniors.  He got … class decided to do an environmental microbial community (metagenomic) soil study in an untouched region of the Everglades, the … address some of the most pressing challenges of our time. For more information, please visit  …

… Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … in natural products as an undergrad. So for me, it was studying sort of the interface of chemistry and biology … environments. And then can we use that, for example, like bioremediation applications? So we have some pathways and …

… now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … Marcy. So I was wondering, how did you get interested in studying natural products?  MARCY: That is a great question …

… of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … quantity and quality has been the rate-limiting step for many projects at the JGI. The quality of the starting … sequencing workflows and provide guidance as to how to perform sample QC prior to shipment: Importance of Sample QC …

… Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … what a specialized metabolite is, then this is the podcast for you. A lot of this is based on a really great paper that … like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can catch him …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … cluster family is a, I think, is a handy unit to be able to study biosynthetic diversity. There is no precise …

… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … based on annotation may not be sufficient. A more recent effort in the Woyke lab is therefore focused on the …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all … of the JGI User Agreement , JGI User Agreement for Federal Agencies , DNA Synthesis Appendix  and DNA …

… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … on DNA sequencing and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a … the production of the natural product. So that was my PhD study, and then towards the end of my PhD study, then …

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … build out much more of an integrative genomics approach to studying environments, studying organisms, to looking at …

… this question in natural soil ecosystems by combining metagenomics with other omics approaches, including … Multiomics approaches such as metagenomics and metatranscriptomics provide invaluable information on virus diversity and activity in microbial … resources. The main focus of these resource development efforts currently include:  in silico host prediction for …

… help with: preparing a Statement of Work, completing a formal User Agreement, and ultimately launching the user’s project. See below for details on each step. … Before work can start on any approved proposal – including the submission of samples for sequencing, or the submission of sequencing data for …