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Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … in natural products as an undergrad. So for me, it was studying sort of the interface of chemistry and biology … environments. And then can we use that, for example, like bioremediation applications? So we have some pathways and …
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… of the process needed to prepare and ship samples for sequencing by the JGI. Additionally it includes … quantity and quality has been the rate-limiting step for many projects at the JGI. The quality of the starting … sequencing workflows and provide guidance as to how to perform sample QC prior to shipment: Importance of Sample QC …
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… now? MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … computational skills among biologists JGI CSP Proposal: Metagenomic mining of natural product diversity and …
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Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … what a specialized metabolite is, then this is the podcast for you. A lot of this is based on a really great paper that … like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can catch him …
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… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … cluster family is a, I think, is a handy unit to be able to study biosynthetic diversity. There is no precise …
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Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all …
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… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … Giant virus diversity and host interactions through global metagenomics.” Nature 578(7795): 432-436 (2020). Seshadri … Tringe S.G., Visel A., Woyke T ., Wang Z. & Rubin E.M. Metagenomic discovery of biomass-degrading genes and genomes …
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… of secondary metabolism. DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … on DNA sequencing and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a … the production of the natural product. So that was my PhD study, and then towards the end of my PhD study, then …
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… viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and … virus biology and diversity in the era of genome-resolved metagenomics. Nature Reviews Microbiology volume 20, 721–736 … The ISME Journal. 8 (8), 1634-1644 … Publications … For further details, please reach out to the Group Lead …
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… to environmental changes. The program lays the groundwork for sustainable solutions to current problems facing … supports the development of next-generation biofuels by studying perennial grasses and fast-growing trees as … in legumes, which can reduce dependence on fertilizers. The study of secondary metabolites enhances our understanding of …
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… partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and spatial … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this … responses … Selected Publications … Research Team Alumni … For further details, please reach out to …
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… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … build out much more of an integrative genomics approach to studying environments, studying organisms, to looking at …
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