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NANCY: My pleasure.   DAN: I guess I wanted to start, maybe just by asking you how did you get into the field of natural … school. And one of the things that I noticed is all the food that the students got was coming from other countries, … that’s of the sort that people are looking for, for biofuel production. We’ll see how that goes.    ALISON: Is this …

… so that we can start to use the DNA sequence to predict or just understand better the language of microbial cell-cell … has done a really nice job of providing that general scientific audience whereas now I’m sitting here with two people … the absence of oxygen. But these are the next step in the food web. So these are organisms– if you think about maybe …

… ’80s. And then the first time we saw the structure that Dan just described to you. So the enediyne referred to two … cell type. So by using the antibody as the recognition motif, coupled with the enediynes, the disease cell killing … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to …

Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong … group . Research Team … Coclet, C. and Roux, S. (2021) Global overview and major challenges of host prediction … (2016) Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses.  Nature . 537:689-93. … …

… this is all explained in detail, so if you’d like a link, just check out the show notes above or at … of a particular part of the Streptomyces phylogenomic tree, then you will be in a position to say, this group of … Dorrestein – the molecular networking, you can have a global view on the chemical diversity of metabolism. We …

… should be coming out on the first Thursday of the month, just like I promised. Now I just have to make this whole “on-time thing” a habit! I’m … understand, can we utilize sequences of these TetRs to identify what molecule might bind them and then allow for their …

… the JGI website at  naturalprodcast.com . Finally, I’ll just mention here that for this interview Alison was not … was mucking around with Bacillus spores for a long time for food spoilage kind of testing, applications. And that’s … dad never forced it on me, but we always had these scientific news magazines lying around at home. And I would just …

… we talked about sponges, go pull a sponge or extract some tree bark. And so you’re just taking something, you’re grinding it up, and then … about what kinds of proteins exist in a cell and identify those proteins that are enzymes that are doing the …

… research.  These efforts include exploration of the global diversity of alternative genetic codes (Science … Reveal Thousands of Small, Novel Genes. Cell 178(5):1245-1259 Nayfach S, et al, (2019) New insights from … of bacterial and archaeal isolates expand coverage of the tree of life.  Nature Biotechnology  35(7):676-683 Schulz …

… through three primary routes:  … The CSP provides the scientific community at large with access to high-throughput … company that recycles carbon emissions to make fuels and chemicals, improving air quality and promoting a … engineer a Clostridium strain for the production of biofuels and bioproducts from low-cost gas feedstock. For more …

… basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary metabolism … it was– well, I think the day your visit was planned was just a few days before the due date. Dan Udwary: Oh, no. … grad student with Michael. And we did it together. Did the global analysis of biosynthetic gene clusters across, well, …

… take for granted nowadays. You know, at that time, it was just [that] the chemistry of organisms was fascinating to … and did some meta-T [meta-transcriptomics] on that and identified just a small subset of transcripts up-regulated … an impact, like the domoic acid story, and be able to have global science-type connections, and be able to use our …