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… science and scientists of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. … on lots of different creatures. And you can find sponges everywhere in the ocean, and most people think of them as …

Sciences. She’s an ethnobotanist and the herbarium curator there, with a broad range of experimental work on plants for … over into the Arabian Peninsula, and then into Europe, and everywhere now. But was there any reward to the people that …

… archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … evolutionary time scales.The Metagenome Program combines large-scale, time-series metagenomic data with detailed … viral ‘dark matter’:   Viruses are abundant in the biosphere and influence microbial dynamics, evolution, and …

… bioeconomy applications. The program provides high-quality, large-scale genomic data to advance microbial research that … associated with microeukaryotes. The program also studies giant viruses. Key research areas include terrestrial …

… from Vanderbilt University’s Chemistry Department, where he is the PI of the Laboratory for Biosynthetic … or through the JGI website at jgi.doe.gov . There’s a lot more to talk about there, and I’ll be getting … active in a heterologous host. So what you really need is a large tool kit of pieces in order to put them together to …

… and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but … into that?  NIGEL MOUNCEY: Secondary metabolism fits everywhere! [LAUGHTER]  DAN: I think it does.  NIGEL …

… to Episode 6 of Natural Prodcast. What you’re going to get here is the very first episode we recorded. You’ll probably … mining together. Marc was the Head of Experimental Genomics there, before he decided to leave for graduate school and … measuring. And that’s because the threat isn’t the same everywhere? It’s not uniform? Is that what it is? MARC: I …

… know me call me Kate. Dan Udwary: Great. So we’ve got Kate here today, and we wanted to talk to her about a whole list … idea of taking all the different natural products data that there is and putting things, coalescing them, so that we can … on so many levels. So first, I mean, all bacteria are everywhere. But the fact that actinomycetes form spores and …

… especially when you’re working in natural products right. There’s many different avenues toward chemistry. But that’s … assays is what those would be. The work that we do at larger scale in order to look at the chemistry a little bit …

… so, especially if English is not your first language, if there’s ever anything you didn’t catch in the audio, head … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to …

… work, in genome mining, we have an awful lot of crossover, where us genome miners get really jazzed about finding … it to be useful? Not in a process chemistry route because there, you just need to build one molecule. But what I would … students to work in my group, it looked like he had like a giant thing of like candy corn on his bench. And I was like, …

Aaron Puri. DAN: Jackie, we have one of your colleagues here today! JACKIE: We do. It is very exciting to have Aaron … turn it over it’ll become covalently bound to it and maybe there will be some a affinity tag or a fluorescent tag, and … or the genes that could encode for that right next to a larger biosynthetic gene cluster the products of the …