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… The focus of this group, in recent years, has been to bring generalizable … with little to no genetic tools enabling heterologous expression and functional exploration.  The developed …

… for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from … my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … explore the regulation of biosynthetic gene cluster expression in organisms. And that’s led by Hiroshi Otani …

… Fine-tuning metabolic gene expression helps identify variants … available for other JGI users outside the realm of bioenergy optimization. Summary Life is all about balance. … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National …

… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, as well as successful submissions to our CSP New Investigator, CSP Functional Genomics, and Facilities Integrating Collaborations for User Science calls. These …

… of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex wiring … — and integrated these data with single-cell gene expression maps. Together, the scale of data enabled by … In addition: Multiplexed barcoding enables the simultaneous profiling of multiple species; stricter filtering criteria …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … antibiotic is really an antibiotic in nature, what is the general belief is that that is the case when there is a …

… right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. This should be coming out on the first … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … that you can turn on the natural product, say clusters or expression systems so that-- BETSY PARKINSON: Exactly. DAN: …

… Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The … (polyploidy) and insights into the dynamics of gene expression as it grows back vigorously year after year … (BER), grant nos. DE-SC0006634 and DE- SC0012379. The generation of the tetraploid M. sacchariflorus whole genome …

… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer … these sgRNAs, cloning them alongside CRISPR-Cas9 into an expression vector to create an sgRNA plasmid library. The …

… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to identify new divergent lineages and expand … complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … it was amazing. And now you have– just to the exponential expression of all these genomes and what can happen with all …

… Panicum hallii genomes offer insights to drought tolerance. The Science Researchers have … grasses using Panicum hallii (Hall’s panicgrass), by generating two complete genomes from varieties that diverged … QTL mapping to find the genomic regions that control gene expression and physiological responses to drought. They …