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… that consists of coordinated hands-on experiments across fungal biology teaching labs. The purpose of the program is to: train students and professors in laboratory techniques … and data analyses compile original data for improving fungal genomic resources empower students through isolation …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans … people looking at sponge chemistry and looking for active compounds and pharmaceuticals. ALISON:  Okay, and he was …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … so enediynes are this really cool class of natural product compounds, Alison. They are – if you can imagine – two … natural products of microbial origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the …

… as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided … below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is complete. Raw metabolomics data is submitted to the  MassIVE repository . Not all products are available …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … episode is our conversation with Nancy Keller, a fantastic fungal natural products researcher from the University of … of mycotoxigenic fungi. It’s actually easier to find new compounds, natural products, in the lab, honestly, by …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … products is an older term for the special, natural chemical compounds that you find in plants, fungi and bacteria, … where this happened have a tendency to be susceptible to a fungal infection of rye grain – a specific fungus, Claviceps …

… in natural products right. There’s many different avenues toward chemistry. But that’s kind of where I had you. How … what we know is they’re quite selective in some way for antifungal activity. They are also, some of them, are … being called an egg defense model. And so maybe there are compounds in there that we know there are compounds in there …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural … uses or applications– are the evolutionary nature of these compounds. At the end of the day, all the content produced … Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a functional role. …

… If you stick around for the next few months, you’re going to hear my last interview with my co-host Alison Takemura, … a big idea that fits within our mission, we’re happy to help you figure out if it’s a good fit. Everyone we talked … And I think also the quality that we provide. So for fungal and for a lot of our eukaryotic genomes, all our …

… Dan Udwary: Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I … as well. A lot of them have looked at applications like biofuels. Dan Udwary: Sure. Kate Duncan: But from a natural … is, do microalgae also produce natural products that can be helpful in producing biofuels? Because you had mentioned …

… The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic biology … Our production group operates as user facility that aims to provide access to state-of-the-art DNA synthesis and … design with scaling the production of large, difficult to synthesize constructs such as those involving biosynthetic …

… . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA synthesis requests, the … request falls below these thresholds, you will need to utilize a core facility instead. Proposals may not exceed … nonpolar metabolomics samples, and should generally conform to the guidelines for our  CSP Large Scale call .  Process …