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Program aims to streamline genome analysis workflows for microbial eukaryotes, build fungal and algal pangenomes, and integrate multi-omics tools to enhance functional studies. These efforts seek to … to sequence 1000 fungal genomes from across the Fungal Tree of Life, from an international research team in …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … associated with the chemistry department as well as the life sciences department. So welcome, Alison to today’s … with. DAN UDWARY: Yeah. ALISON NARAYAN: And there are other tools that I think are really useful, that again are set up …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … advanced mass spectrometry techniques and computational tools, the program supports foundational research related to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that …

… innovative screening technologies and computational tools that enhance biofuel production and biosystem design. … economy. … Genome to Enzymes and Pathways focuses on discovering and characterizing enzymes and pathways vital to … … Synthesis Capabilities & Offerings … BOOST … Integrated Microbial Genomes and Microbiomes … Mycocosm … Phytozome … …

So I was always an outdoorsy kid – I was often found in a tree or covered in dirt playing with my dog in the yard. But … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… biofuels by studying perennial grasses and fast-growing trees as renewable energy feedstocks. It also tackles … development of complex biomolecules — which can include antimicrobial and anti-pest compounds.  The program is working … behind phenotypic evolution. It also utilizes advanced tools, including deep learning algorithms for gene …

… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … using these together along with all of our computational tools to really build out much more of an integrative …

… program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will … work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … insights from sequence data, employing IMG data and tools for comparative analysis, visualization and …

… genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to … collect microorganisms all over the world for the sake of discovering biologically active natural products.  DAN: …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … support users, our efforts include developing computational tools for predicting biosynthetic gene clusters (BGCs), … biosynthetic gene clusters (BGCs) across all kingdoms of life. Tools are provided to display annotation data from …

… of thought with that. So some people are interested in cave microbial– people are interested in the more extreme … ecology, because we feel as though that stacks the deck for discovering molecules that do something. And that’s a whole … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …