Search

… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties … within those genomes. Our aim is to more fully capture microbial and viral diversity, leading to a better …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that …

… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … associated with the chemistry department as well as the life sciences department. So welcome, Alison to today’s … with. DAN UDWARY: Yeah. ALISON NARAYAN: And there are other tools that I think are really useful, that again are set up …

… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … advanced mass spectrometry techniques and computational tools, the program supports foundational research related to …

… The DNA Synthesis Science User Advisory Committee is chartered by the Program … on the effective management and strategic objectives of the programs. The Committee serves as the Program's key external advisory panel and advocates of Program strategy, operations, and scientific relevance …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of biofuels, biochemicals and other bioenergy solutions.  … innovative screening technologies and computational tools that enhance biofuel production and biosystem design. …

… So I was always an outdoorsy kid – I was often found in a tree or covered in dirt playing with my dog in the yard. But … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … behind phenotypic evolution. It also utilizes advanced tools, including deep learning algorithms for gene …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and …

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … using these together along with all of our computational tools to really build out much more of an integrative …

… genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to … collect microorganisms all over the world for the sake of discovering biologically active natural products.  DAN: …

… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … their potential applications in the bioeconomy including biofuels, biochemicals and sustainable agriculture. …