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… cycling and bioproduct applications.  The team has three subgroups: Synthetic Biology Lab : a user science group … develops data science tools for workflow management and novel automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables …

… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … most pressing challenges. … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and …

Biology lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA … as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … applications.  We are interested in:  characterizing novel enzymatic activities using phylogenomic driven …

… it was a very exciting event. And people in the research group would pore over it and argue about it and think about … you’re interested in improving a lead compound that you’ve discovered from microbes. Chances are you could find a dozen … in order to put them together to build pathways, to make novel compounds, or to find analogs. And that was Warp …

… an exploration into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a … me to ask a simple question. In 1929, Alexander Fleming discovered a molecule called penicillin. And this was– maybe … We found that there were new genera, these basic taxonomic group called the genus. We found there were new genera in …

JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single … to the nucleocytoplasmic large DNA viruses (NCLDV) supergroup. The expansion of the diversity for large and giant … researchers previously applied this approach to uncover a novel group of giant viruses dubbed “Klosneuviruses.” …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … and he arranged funding to do it nonetheless from his own group’s funds. So I could start that project, and I was … time called Genbiotics , which was a large program to find novel antibiotics. And this particular project focused …

… at the University that I was at that did just this. And I discovered it was called “marine natural products.” And that … Association for Marine Science. And then I started my own group in 2016. And it very much ties in all of those … currently exist. We looked at chemistry, so it’s really novel. And they’re just really exciting. And it really kind …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … which stands for International Cooperative Biodiversity Groups, and it’s this great program funded by the National … ordered way for perhaps 80 years. And in that time, we have discovered many thousands of different natural product …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … desired chemicals. … The JGI's DNA Synthesis Science Group supports researchers exploring how to convert sequence … relationships as well as insights into clade-specific novelties and expansions.  … ICE is an open source registry …

Hey, everyone! Welcome to the “Self Promotion Episode” of Natural Prodcast. A little bit of a bonus episode, since … along the journey. And so I started my PhD in Brad Moore’s group and joined his lab when he was at University of … seems to be a new structure, and the microorganisms are novel. I mean, we have Streptomyces , but they’re new …

… had two major natural products projects that we had in my group which was bioengineering bio-process R&D, BBRD, a … up to supporting 200,000-liter fermenters.  DAN: Was that discovered there or did it start–  NIGEL MOUNCEY: The … secondary metabolism analysis and research as a driver for novel technologies that can serve all JGI users. Nigel has a …