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… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … I’m so excited about my lab’s robot is that it gives us a tool to help us– DAN UDWARY: You can generate that data. …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I … products field as it relates to structure elucidation and genome mining, and how we might start to better connect … we’re now very much – we’re interested in how we can build tools which will let us see the whole landscape of natural …

… Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … lab, I worked on identifying and characterizing haloperoxidases from bacteria. And with Christian, I started getting a … of always working on natural products but just different tools and how to really access and manipulate these pathways …

… discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … insights into viral evolution and complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds in the … States. They also provided multiple access points to the information. The team harnessed a community-science program to … State University. A portion of this work was also performed under a subcontract from the River Corridor Science …

… them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the molecular … advanced mass spectrometry techniques and computational tools, the program supports foundational research related to … biogeochemical processes, development of high performance plants and microbes, and understanding microbiome …

… vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … fungal and algal pangenomes, and integrate multi-omics tools to enhance functional studies. These efforts seek to …

… algae and plants. These molecules, which are not essential for fundamental growth, provide critical advantages to the … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop enhancement. The … support users, our efforts include developing computational tools for predicting biosynthetic gene clusters (BGCs), …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … DAN: Welcome back to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting some conversations … from the University of Wisconsin, recorded at the Society for Industrial Microbiology (SIMB) Natural Products meeting …

… I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. This week, we have our … learn how to make peptides, rationally. We’d find these tools, we’d understand them, and we’d apply them. And so, I …

… to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data … discoverability and accessibility are critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for further …