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… discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … insights into viral evolution and complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the molecular … advanced mass spectrometry techniques and computational tools, the program supports foundational research related to … biogeochemical processes, development of high performance plants and microbes, and understanding microbiome …

… vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … fungal and algal pangenomes, and integrate multi-omics tools to enhance functional studies. These efforts seek to …

… algae and plants. These molecules, which are not essential for fundamental growth, provide critical advantages to the … and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop enhancement. The … support users, our efforts include developing computational tools for predicting biosynthetic gene clusters (BGCs), …

… Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … lab, I worked on identifying and characterizing haloperoxidases from bacteria. And with Christian, I started getting a … of always working on natural products but just different tools and how to really access and manipulate these pathways …

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot … research lab all the way from Ambr250 fermenters to 2 liter Dasket fermenters to 30 liter Sartorius stainless steel … using these together along with all of our computational tools to really build out much more of an integrative …

… to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data … discoverability and accessibility are critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for further …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will … to the  MassIVE repository . Not all products are available for all proposal calls.   Please review the call language …

… An assay used for profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … samples in 96-well plates on automated liquid handler platforms, substantially increasing efficiency and scalability. … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I … products field as it relates to structure elucidation and genome mining, and how we might start to better connect … we’re now very much – we’re interested in how we can build tools which will let us see the whole landscape of natural …

… I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… insights into environmental tendencies The Science The  Metagenome Stability Diagram — a tool within the Integrated Microbial Genomes and Microbiomes (IMG/M) platform — has been developed to help inform scientists and … The work conducted by the US Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE Office …