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… target is based on 98% of the total available hours.   FY 2021 DOE Metrics There were 2,180 unique* JGI users in FY2021 , which includes Principal Investigators (PIs), Co-PIs, … % of Goal Goal (hours)** Actual Total Actual % Goal FY 2021 Total 250.0 467.195 187% 8,760 8,568 99.8% Q1 2021 …

ZIEMERT: Big picture, I want to understand how secondary metabolites evolve– who makes them, how do they spread, why do they spread in a certain way from one bacteria to another, how do they change then, and why are … We smell them, right? We drink them. I mean, secondary metabolites, natural products, caffeine, all that stuff …

… of the Joint Genome Institute and head of the Secondary Metabolites Science Program at JGI, and also my boss, Nigel … we partnered with a company in Japan, Meiji Seika Pharma, transferred the technology that they developed over to Dow … Non-model Bacteria Check out the agenda for the JGI’s 2021 Annual Genomics of Energy & Environment Meeting   …

… and comparative analysis of thousands of archaeal and bacterial type strains ( GEBA-type strains project ), the … bacteriophages. Cell . 185(21):4023-4037 Nayfach S, et al. (2021) Metagenomic compendium of 189,680 DNA viruses from the … Nat Microbiol . 6(7):960-970. Nayfach S, et al. (2021) CheckV assesses the quality and completeness of …

Scripps. So we’re looking at biosynthesis of marine fungal metabolites. We’re also looking– now we’re started a newer … So we’re now trying to see the implications of those effects and how that compares to Owens Lake in California … has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it …

… can you tell me the story of how you got into secondary metabolites? Kate Duncan: So I always liked science in … their ability to evolve, to go with horizontal gene transfer and run with it and produce different chemistry. … conditions, oxygen conditions. Don’t get me started about temperature and all the rest, right. So you’ve only got, …

… to the user and no granting of funds.   Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics Status CLOSED CLOSED ONGOING ONGOING …

… genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables … Program is focused on understanding the critical roles of metabolites in living systems, particularly as they relate … ecosystems. Identifying and analyzing primary and secondary metabolites helps uncover their roles in processes such as …

FY22 and later through the Community Science Program (CSP), Facilities Integrating Collaborations for User Science … for which JGI has not yet received samples as of Sep 30, 2021 are subject to a 2-year embargo to maintain the … Data from projects that received samples before Sep 30, 2021 and are ongoing are subject to the 2-year …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … So you know it’s not doing harm and there aren’t side effects. ALISON: Yeah, I guess you’d use something like a … the genes that code for the proteins that produce secondary metabolites. Do you recognize this? DNA 🡺 RNA 🡺 Protein …

And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more progress faster, … are built up from amino acids, so they’re secondary metabolite peptides. And there are two ways that nature does … with macro-organisms that produce most secondary metabolites. If you’d like to read more about this, I highly …

Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets … interest is understanding the distributed and dynamic metabolite networks of environmental microbes and how they …