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… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use … the fascinating world of giant viruses, which challenge our understanding of viral complexity and evolution Our research … Understanding the complex relationships between microbes and …

… target is based on 98% of the total available hours.   FY 2020 DOE Metrics There were 2,038 unique* JGI users in FY2020 , which includes Principal Investigators (PIs), Co-PIs, … Goal   Goal (hours)**   Actual Total   Actual % Goal   FY 2020 Total   250.0 290.492 116% 7,932 5,616 70.8% Q1 2020 …

… he has an accent, and, so, I don’t really have any trouble understanding him, but I know from the download stats that … compounds, Alison. They are – if you can imagine – two carbons in a triple bond attached to two carbons in a double bond attached to two carbons in a triple …

… pathways, which led her to a successfully funded JGI CSP project. And we also got to talk about work at her … can do these small rings, and so I think we need a better understanding of that. We have a crystal structure, and … fun that we've started that is a different subject is from microbes to medicine labs. So this is-- we've been working …

… of this is based on a really great paper that came out in 2020 where this is all explained in detail, so if you’d like … terms of the definitions, such that everybody could have a understanding of what we’re talking about. And while … about it, the only way a primary metabolite or a primary metabolic pathway is good for anything, it is if the final …

… has recognized how important natural products are to understanding the natural environment, and so our Director, … was adjacent to what I worked on, but my experience of how microbes are interacting in the environment like, like my … gene clusters and to do research to get a better understanding of that data. ALISON: Awesome. So tell me why …

… has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it … was the Salinispora genome project. And that was a JGI CSP project. They sequenced that genome for us at a time … that system is just not possible from– completely understanding the system is not possible from the tools that …

… global challenges by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, … The Plant Program advances our understanding of plants’ biological and ecological roles to … energy into chemical energy — and its implications for carbon sequestration, renewable energy and agricultural …

… and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in the group include … resistance. Cell . 184(13):3376-3393 Almeida A, et al. (2020) A unified catalog of 204,938 reference genomes from … Kyrpides NC. et al. (2016) Microbiome Data Science: Understanding Our Microbial Planet. Trends Microbiol. …

… metabolomics enables functional genome annotation, improves understanding of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and leads to the discovery of new molecules and … variety of experimental samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well …

… activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined … bobtail squid, it’s doing some sort of interaction with its microbes that it’s getting.  But yet the organisms are … those numbers are still actually pretty high in terms of understanding from just sequence gazing alone what those …

… conference, which took place a few weeks ago, in January of 2020. So, you might hear us referencing a conference, and … use natural products necessarily. Fungi are large. They’re microbes, but they’re large microbes. And they have all sorts of cool phenotypes that …