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Lab Intellectual Property Office to facilitate these new interactions.  The PDT enables industry engagement through three primary routes:  … The CSP provides the scientific community at large with access … right, title, and interest to any intellectual property generated under the agreement. … CRADAs enable research …

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use … 255-255 Schulz et al. (2020) Giant virus diversity and host interactions through global metagenomics. Nature. 578 … binning of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature …

… focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … Kyrpides N. C., Woyke T . Giant virus diversity and host interactions through global metagenomics.” Nature 578(7795): … the Hungate1000 Collection.” Nat Biotechnol 36(4): 359-367 (2018). Woyke T ., Doud D. F. R., Schulz F. The trajectory of …

… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it … of Utah , about her secondary metabolism research on novel microbes and bioactive compounds in the Great Salt Lake. …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … a nice example of going from a whole community with many microbes, hundreds of gene clusters, and then being able to … that the expression of these gene clusters play in these interactions. But also things like trying to predict at …

… advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … along with their associated viruses and mobile genetic elements. Beyond exploring and characterizing … ecosystems.  By studying microbial communities and their interactions, the Program aims to unlock the fundamental …

Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As much as we … products is that we don’t know what all the biosynthetic gene clusters look like.  DAN: For sure.  MARCY: We have so … on increasing computational skills among biologists JGI CSP Proposal: Metagenomic mining of natural product …

… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … NIGEL MOUNCEY: Yeah, so we put out a strategic plan in 2018. And in building that plan, we thought about secondary … But they really span our core science programs which are microbes, and fungi, and algae plants, synthetic biology. …

… genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something … systems. No one was, at that time, really working with microbes from the ocean. So I felt there was a wonderful … JGI projects over the years starting with, you know, the CSP that we did and then leading up to today to some …

It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … them on a regular basis. So they are full of terrestrial microbes. So they’re open ecosystems. They’re not sealed off … in the cave project just now switching from intermicrobial interactions, studying intermicrobial interactions by …

… and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … then we were using these probes to look at host pathogen interactions mostly with like enteric bacteria. And I really … ecology community to be able to better predict how their microbes are interacting with each other from sequence …

… to the user and no granting of funds.   Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics Status CLOSED CLOSED ONGOING ONGOING …