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… is that you could, therefore, expect a lot of chemical diversity. So many compounds will fulfill the same function. … about it, the only way a primary metabolite or a primary metabolic pathway is good for anything, it is if the final … or specialized metabolism, what we are often coming across is very complicated pathways with many, many enzymes, …

… one of the best things that we do is work with this really great group of biologists that know what they’re doing much … postdoc Panama as part of the international cooperative biodiversity group (ICBG) based in Panama and was dual there … they don’t transfer a lot of DNA back and forth, especially across species. And so then there isn’t horizontal transfer …

… fundamental things, like, are we waking them up? Are they metabolically active and slowly ticking away at these … then, chemistry-wise, they’re the stars, right? Chemical diversity, the sheer number of chemicals they produce, their … in Antarctica on a ship. Yeah, so I went to Antarctica in 2018 as a participant in Homeward Bound 2, last year as …

… be back in a room with you, Dan. And to be actually sitting across the table from you.  DAN: Absolutely. It’s been a … NIGEL MOUNCEY: Yeah, so we put out a strategic plan in 2018. And in building that plan, we thought about secondary … A few examples of those are obviously expanding the diversity of known secondary metabolites and their …

… elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses several … experimental approaches to assess microbial activity across ecosystems.  By studying microbial communities and … research provides insights into microbial diversity and metabolic potential, with implications for energy …

… But we’re not just here to talk about us. We have a great person to talk to tonight. We have Nadine Ziemert from … see. So it doesn’t seem to be a correlation between biodiversity in taxa and biodiversity in secondary metabolites. So stuff like that, I … area of natural products. For further reading she has some great reviews in the field, and I’m looking forward to …

… of challenges that usually lead to surprises and really great discoveries! And Eric’s done an awesome job, in that … with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the … backbones, and so that’s our specialty. That’s where most diversity of life on earth is located. ALISON:  Have you …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for … and advanced genomic analysis to explore the rich diversity of fungi and algae. These organisms play a … The program’s fungal genomics research explores new metabolic processes and enzymes that can be applied in …

… Two fanatic PhD students. Alison Takemura: It sounds great. Yeah, it sounds like it was really needed at that … Did the global analysis of biosynthetic gene clusters across, well, at that time, all genomes that were out there. … you to get a bird’s-eye perspective on the biosynthetic diversity element of these genomes. And you see how they’re– …

… and where we are today. After that, we have lots of great conversations that we’ve already recorded with some … the context for their work is.  ALISON: Cool. That sounds great. I’m so glad that you invited me to have this … be so mind bending and that we might just kind of happen across them in our food. That’s crazy!  DAN: Yeah, just like …

… the answer would be that there’s actually a great deal of diversity within these methanotrophs for example, that are … me in the woods then. [LAUGHTER] JACKIE: So we’re kind of across — covered quite a few different topics. And so right … people doing this but we are very interested in looking at metabolic diversity and new metabolic niches to try to find …

… this we’re going to be spending some time talking some great scientists, who all have really interesting stories … – that there are some very specific patterns and shared DNA across all of these things. It turns out secondary … to be here and be able to discuss this incredible, natural diversity that we have at our fingertips. So I’m very …