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The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … And one would envision that microorganisms have evolved multiple variations of these compounds. And so if you’re …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … the metabolome into well plates. And we can use our fancy multiplexed activity metabolomics method to tell us what’s …

Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing to enable biological discovery by the … to increase sequencing output while significantly lowering costs. Staff process samples, perform quality checks, and …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … could have arisen from. DAN UDWARY: OK, so sort of a phylogenetic reconstruction kind of a thing. ALISON NARAYAN: … using ancestral sequence reconstruction”,  PNAS.  2023,  120, e2218248120. doi : 10.1073/pnas.2218248120 …

…   Gain access to omics technologies generating community data at zero cost —  submit a proposal.  …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … a review paper of actinobacteria, some advances. All the authors and that are PhD students. And I think it’s a really …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … then we can say, OK, there is an expansion, you have two copies. And then you ask the question of whether that second …

Prodcast episode 17. The guest we have this week is Professor Cassandra Quave from Emory University, with joint … bioprospecting vs biopiracy, early stage drug discovery in general, and a possible data-driven future for plant natural … compound is not the answer. Some cases, it’s actually multiple compounds acting in synergy which is scientifically …

… resides on a computer system funded by the U.S. Department of Energy. Anyone using this system consents to monitoring … or the University of California. The views and opinions of authors expressed herein do not necessarily state or reflect … and any statement of authorship are reproduced on all copies. JGI is not responsible for the contents of any …

Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to … of certain types of data to support their use by those generating data. The JGI Data Policy applies to research … use-restricted data. JGI proposals typically include multiple projects of different types which can span several …