Search

… … DAN UDWARY: You’re listening to the Department of Energy … Alanjary and Tilmann Weber to be a really valuable piece that shaped my thoughts about the history of genome mining … And then you search for – re-search for these biosynthetic enzymes that we think must be similar within the fosmid …

… … DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion … cool. The vanadium haloperoxidases are some really cool enzymes, and it was fun to see that project take shape. … JACLYN WINTER: So I actually– well, I mean, not having family in science, it was hard to see what are the different …

… … DAN: You’re listening to the US Department of Energy Joint … working on harder organisms, with the kinds of challenges that usually lead to surprises and really great discoveries! … the “Non-Ribosomal Peptide Synthetases” or NRPSs. These are enzyme systems that grab amino acids and stick them together …

Office of Science user facility supported by the Biological and Environmental Research program, the Joint Genome … and synthesis, metabolomics and computational analysis that enable systems-based scientific approaches to these … metabolism necessary to design communities, new strains, or enzymes to convert plant biomass components into fuels, …

… … DAN: You’re listening to the US Department of Energy Joint … structure – the enediyne compound that people know, as a family, it’s more than 7 decades. So, this family of … why the stereochemistry was that way. And he told me, it’s enzymes. It’s magic.  BEN:  Yeah, right.  DAN: I thought …

… … DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it … it interacting with, like, a binding pocket for one of the enzymes, so something that’s metal dependent? Is it– and we … of Microbiology and Immunology , and we wish her and her family all the best during that transition. In this episode, …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you … 20S proteasome. The proteasome in the cell is a bundle of enzymes that is used to degrade proteins, peptides, that are … studied two strains. One was a new order, and one was a new family. And these two microbes produced new alkaloids, …

… … DAN: You’re listening to the US. .Department of Energy Joint … the very first episode we recorded. You’ll probably notice that the audio quality isn’t as good as what you’ll hear in … when you’re in a community? How is the microbiome being shaped by different types of secondary metabolites? How does …

… … DAN: You’re listening to the US Department of Energy Joint … backbone gene synthases, but having a different decoration enzyme actually could give you something that’s quite … have on cluster sets that are sort of the same. You know, family clusters, like if you looked at the statins, you …

… … DAN: All right. Welcome back to Natural Prodcast. I did it. … this whole “on-time thing” a habit! I’m really not good at that, you guys. I’m trying really hard just for you. And the … But on the other hand, we're also really interested in enzymes to do some of the reactions that chemists find …

… … Dan Udwary: Hey everybody! Welcome back for Natural Prodcast … discovery. It’s also the kind of book we can hand off to family members and friends as a way to introduce them to the … Usually when we do these interviews, most of the people that I think we’ve talked to so far I either know …

… … Dan Udwary: Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today … goodness. I mean, if you were to find my scientific papers, that would be Katherine. Dan Udwary: Right. Kate Duncan: But … She talks to lots of great scientists outside of secondary metabolism, and if you like what we’re doing here, you’ll …