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… acids (aa) in size, half that of previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It … out that some of these were shorter than the typical Cas12d proteins and were also found next to cas1 genes. Further …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … University, was released to the public in a highly-cited 2006 publication in the journal Science . This provided a … 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …

… seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … with the National Cancer Institute who had a panel of 60 different cancer cell lines. And we would send them these … using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with everything that’s known. So …

… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …

… CSP Large-Scale LOI #2 … FICUS Example #2 …

… American Academy of Microbiology (AAM) ! She is among the 68 new Fellows in the Class of 2020, selected from 118 … the AAM Fellows in this cohort. Go here for the full AAM news release. Woyke is also one of the organizers for the …

… Notices Data Portal files will be inaccessible July 22–July 24 for computing upgrades . We regret any inconvenience. Effective July 27, 2026, the JGI will move to a new login service, requiring the … Portal was replaced with the Data Portal and sunset in 2026. The Genome Portal was designed to provide unified access …

… the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of … dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. (2023) Identification …

… Serve the Changing Planet (download a copy at jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of … In service of solutions that will impact society, the 2024 strategic plan introduces the JGI’s new vision to lead …

… [DNA Synthesis Science Head] Yasuo [Yoshikuni] gave back in 2016.” Alper’s first approved JGI proposal came through the … development and its applications. “I moved to UC Davis in 2014,” recalled Philipp Zerbe of the University of …