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Mining Metagenomes for Cas Proteins
… is now at Tel Aviv University. The Cas14 proteins are ~400–700 amino acids (aa) in size, half that of previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …
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Complete genome sequence of Enterobacter sp. IIT-BT 08: A potential microbial strain for high rate hydrogen production
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Natural Prodcast Episode 19: Bill Fenical
… about why the ocean was basically unexplored until the 70s, and how diving was the catalyst of that. We also talk … seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, …
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Secondary Metabolites Program
… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …
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Examples: Successful LOIs & Submissions
… CSP Large-Scale LOI #2 … FICUS Example #2 …
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Data Ecosystem
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Tanja Woyke Elected to American Academy of Microbiology
… (AAM) ! She is among the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for … the AAM Fellows in this cohort. Go here for the full AAM news release. Woyke is also one of the organizers for the …
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Events
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JGI Portals
… Portal was replaced with the Data Portal and sunset in 2026. The Genome Portal was designed to provide unified access … and analytical tools for all JGI sequencing projects. In 2021, the JGI launched the Data Portal to eventually replace …
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Microbiome Data Science Team
… the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of new genes with … Pavlopoulos GA et al. (2023) Unraveling the functional dark matter through global …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… Serve the Changing Planet (download a copy at jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of … In service of solutions that will impact society, the 2024 strategic plan introduces the JGI’s new vision to lead …
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