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… aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It … out that some of these were shorter than the typical Cas12d proteins and were also found next to cas1 genes. Further … the US Department of Energy under contract no. DE-AC02-05CH11231. The work was supported in part by grants from the Paul …

… an international ambassador? MARC: Yeah, I believe it was 2012 when she started this at Yale, and she only had six … that’s really popped up at funding agencies and the popular news recently because a lot of soldiers in the Iraq and …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed … access to the whole sigma catalog of precursors in their 12C form. You can feed those and look for incorporation in … would grow up our bacteria on 13C methane or methanol, feed 12C methionine, and we were able to pull out the quorum …

… from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, U. … ecosystem. Microbiome 11, 237. https://doi.org/10.1186/s40168-023-01666-z Neri U., Wolf, Y., Roux S., Camargo A.P., … of hypermutation in the global microbiome. Nat Commun 12, 3076. https://doi.org/10.1038/s41467-021-23402-7 Roux, …

… 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY PARKINSON: Very, very-- … what was really interesting is when I started my lab in 2018, several papers came out right in a row all about this … the issues is in order to make the tetrapeptide, that's a 12 membered ring. And there's extreme ring strain in 12 …

… inside them. And this was, I think it must’ve been about 2001, maybe, and so it was before smartphones and before … women get selected each year as a cohort to experience this 12-months leadership program, of which the last month is in … 3. And I currently co-leading the science program for the 12-months for Homeward Bound 5 and was meant to be in …

… mechanisms of pathogenesis . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …