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… on the amazing John Faulkner’s work, who passed away about 17 years ago now. It looked really interesting. He was … But, say, the last time I checked, it was on the order of 10,000 species. And whenever you’re talking about a new …
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… Wisconsin. Like we discussed in the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should … first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … do you check if they’re there? Like we always talk about 16S for bacteria, but we don’t talk about it so easily with …
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… Cas14 proteins discovered from JGI’s IMG/M database and … report the identification of active Cas enzymes – dubbed Cas14 – that target ssDNA. In contrast, the seminal Cas9 … while Burstein is now at Tel Aviv University. The Cas14 proteins are ~400–700 amino acids (aa) in size, half that …
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… relative of SOD is P. infestans , responsible for the mid-19th century Irish potato famine. Shortly before the … 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …
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… inside them. And this was, I think it must’ve been about 2001, maybe, and so it was before smartphones and before … I went to University when I was quite young. I just turned 17 when I enrolled into University, so I guess I must’ve … going to learn microbiology. So I went to– this was in 2008 by then. And I’ve never done– I mean, I think I did maybe …
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… that there was almost nothing. Now, this is back in the 1970s. So, I thought to myself, maybe I can use my … natural products in the ocean weren’t studied up until the 1970s. You know, I mean, people knew about plants’ chemistry … were not very prolific. We have a collection now of about 17,000 organisms we’ve isolated from sediments, bottom mud, …
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… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …
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… CSP Large Scale Proposal #1 … CSP Large-Scale LOI #1 … FICUS Example #1 …
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