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… coming up with new chemical compounds as well, getting the phase I trials, phase II trials. And at the time, nobody was … of thought with that. So some people are interested in cave microbial– people are interested in the more extreme … that if you looked at the grant applications for the last 40 years for studying biosynthetic pathways, all of them …

… time. And I’m happy to say that we now have two drugs in phase III clinical trials for cancer, two different kinds of … powerful people. These were people that really controlled microbial drug discovery. And a guy like me, with no … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … for uncultivated phages.  Current Opinion in Virology .  49 , 117-126 Berg, M. and Roux, S. (2021) Extreme dimensions … can tailed phages be?  Nature Reviews Microbiology.   19 , 407 Berg, M. et al. (2021) Host population diversity as a …

… demands of our users. … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to … provides tools for analyzing the functional capability of microbial communities based on their metagenome sequence, in …

… there have been huge advances in both. The cool thing about genomes is you can, well, if your assembly is good, you can … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is … of new chemistry, and we want to understand the antimicrobial-resistant era, we need new chemistry. If we want …

Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge … technology in order to enhance the quality of single-cell genomes and directly link functional information with … To provide additional functional insights into microbial genomes, the JGI now uses laser microdissection to …

… and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … IMG kind of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial … can convince them of course. So that needs, also, this seed phase where you really need to get the input already from a …

… development of complex biomolecules — which can include antimicrobial and anti-pest compounds.  The program is working … interactions, focusing on how environmental stress and microbial communities affect plant growth and productivity. … and environmental sustainability. … Plant Flagship Genomes are selected through discussion with the JGI Plant …

… the secondary metabolism side of things was looking at genomes and seeing where the really hard things to sequence … in about a year’s time, we’d be doing a rate of around 1000 genomes per year and an order of magnitude more than … Canada. I just got back from a conference in Canada on antimicrobial resistance sponsored by the Garner foundation. And …

Tijana Glavina del Rio Metagenomics         Danielle Graham Microbial Program Nancy Hammon Workflow Planning Manager …

… the user programs at the JGI, and I’m also the head of the microbial genome program. And I’m a scientist here. And have … for you, we sequenced thousands for you or thousands metagenomes. And I think also the quality that we provide. So … than less. Also, they ask if they can do the project in phases, which is absolutely a possibility. So if they want …

… four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal … Francis Martin will be a keynote speaker at the 2024 DOE Joint Genome Institute (JGI) Annual Genomics of Energy …