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… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … regions of interest and gene copy number variation across multiple genomes. It provides the ability to discover …

Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … enzymes to support mission-driven research. Rapid Metabolic Engineering: Metabolic engineering traditionally utilizes a …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … including understanding enzymatic transformations, pathways, and how changes in metabolism can affect ecosystem …

Sample and library preparation, DNA synthesis and pathway engineering Mass spectrometry based metabolomics … percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, …

It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … we built this as a platform that allows us for– it’s geared toward mammalian systems. But it allows us to assay on a … the metabolome into well plates. And we can use our fancy multiplexed activity metabolomics method to tell us what’s …

… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … me really interested in microbial gene regulation and some pathways. And I thought I’d take an academic job then, but I … products projects that we had in my group which was bioengineering bio-process R&D, BBRD, a group of about 75 …

… conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … of cells and allow for substrates to be directed towards secondary metabolite synthesis. We are currently … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient … user project design, assembly, and quality control Strain Engineering Group : a research & development group and …

The focus of this group, in recent years, has been to bring generalizable … to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and …

… single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … approach, we employ various omics technologies, strain engineering and experimental characterization methods, in … model system by identifying phages and characterizing this multipartite phenomenon in additional plant and bacterial …

… bioprospecting vs biopiracy, early stage drug discovery in general, and a possible data-driven future for plant natural … that they make? CASSANDRA QUAVE: Yeah, so I mean my path towards natural products and medical ethnobotany really … compound is not the answer. Some cases, it’s actually multiple compounds acting in synergy which is scientifically …

… in natural products right. There’s many different avenues toward chemistry. But that’s kind of where I had you. How … garden ant as well as the American honeybee. And so I have multiple opinions which I’m never short of but. In terms of … products is that we don’t know what all the biosynthetic gene clusters look like.  DAN: For sure.  MARCY: We have so …