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… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of … ISME J.   15 , 1569–1584 Roux, S. et al. (2019) Cryptic inoviruses revealed as pervasive in bacteria and archaea across …

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature Communications. 9 (1), 1-9 Schulz et al. … in cell biology. 25 (6), 339-346 Schulz et al. (2015) Marine amoebae with cytoplasmic and perinuclear symbionts …

… of Oceanography in San Diego. Bill is a pioneer of marine natural products, getting into the ocean and looking … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc … to create a program that involves researching the local marine environment. I went out and picked up marine plants, …

… archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … microbial lineages. Charting viral ‘dark matter’:   Viruses are abundant in the biosphere and influence …

… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, …

… quality. Yeah, for sure. NADINE ZIEMERT: Yeah, Dan… it’s a marine actinomycete bacterium. So they look kind of like … only grow in saltwater. So we’re thinking they’re obligate marine. There’s so far no species or no strains known that … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …

… wouldn’t it be cool to look at these– it was actually marine invertebrates there– but look at these things in the … was at that did just this. And I discovered it was called “marine natural products.” And that person was Professor … enthusiastic and gave me a bunch of books, but not books on marine natural products, as such, but things like “Silent …

… grade list of goals in life: on that list are being a marine biologist and being a chemist, and it’s actually … of your research? I know you’ve generally worked in various marine organisms. Except during the time that we worked in … of the compounds that I thought was really cool – found in marine animals – was a peptide. And we had no idea how it …

Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it … how virus infections cause significant metabolic changes in marine microbes, the answer is no. They refer to the … Melissa Duhaime and The Ohio State University’s Matt Sullivan used an experimental approach with a marine …

… genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct …