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Metabolomics Program
The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … metabolomics with genomic data to gain insights into how small molecules function within plants, microbes, and … of environments. ENVnet allows us to uncover globally distributed molecules with conserved structures, offering fresh …
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Natural Prodcast Episode 3: The Primer, Part 3
… side of the field, and it’s a little hard to find in print, but we live in the information age and the ebook version is … parallel with that, the field of molecular biology got more sophisticated around the 80s and the 90s. And so we started … of enzymes and sometimes those are referred to as “small molecules” because proteins are actually molecules …
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Natural Prodcast Episode 9: Roger Linington
… as an expert in natural product structure elucidation, but more recently, he’s been leading an effort to build The … Panama, straight out of my graduate school, and was given a small lab in the National Science Center there and ran this … it gave us a basal training set we could use to build more sophisticated tools, because now we had a very reasonably …
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Plant Program
… plants are a major source of chemical production and contribute to a healthier planet and a thriving future. … The … The pangenomes enable the exploration and identification of small and large structural variation — this variation drives … processes through model laboratory ecosystems. They are small plastic growth chambers where plants grow without …
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Metabolomics
… genome annotation, improves understanding of the role small molecules play in diverse biological systems, sheds …
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Partnerships: Myco-Ed
… genomics. Myco-Ed aims to integrate real scientific contributions/discoveries into undergraduate teaching laboratories … supports the annotation, comparative analysis, and distribution of fungal genome datasets. It includes JGI-sequenced … that leverages scalable computing infrastructure to perform sophisticated systems biology analyses. The platform is a …
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How to Submit Sequencing Samples
Sample QC Protocol JGI’s Total RNA Sample QC Protocol JGI’s Small RNA Sample QC Protocol DNA Extraction 101 : tips, … that you are interested in, then click the blue “reports” button on the right side. The Project Overview report …
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Natural Prodcast Episode 5: Brad Moore
… fun of me a lot, though I actually edited most of that out. But anyway, here’s our conversation with one of my favorite … So we began to sequence that genome – it was a relatively small genome, about five and a half million base pairs. It … that was new, right? Like, my god 10% of the genome makes small molecules that have, you know, new chemistry? That was …
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Natural Prodcast Episode 16: Marcy Balunas
… right. There’s many different avenues toward chemistry. But that’s kind of where I had you. How would you describe … chemistry but I think that’s not necessarily – There are small molecules that host make as well. And so hosts and … metals they’ll kill the bacteria. But if you use really a small amount of them the chemistry that you see changes …
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Boosting Small Molecule Production in Super “Soup”
… approach that starts with engineered yeast cells but then moves out of the cell structure into a cell-free … grams per Liter-hour in a system optimized for developing small-scale prototypes. Additionally, the team also used a similar rewiring strategy to produce the small molecules glycerol and itaconic acid to see how the …
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Natural Prodcast Episode 17: Cassandra Quave
… know through professional circles in some way or another. But today, we have someone who, weirdly, I haven’t, I think, … heard of anthropology. This is– I grew up in a very rural, small town. We didn’t have AP or IB courses or any of these … bugs out of that or whatever. And so I was intrigued by the small section in the book about the conflicts between ideas …
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Natural Prodcast Episode 8: Eric Schmidt
… which is a liver toxin when humans accidentally eat it, but it has a really fun and interesting biosynthetic … chains of amino acids. “Peptide” is just another word for a small protein. And it turns out that a lot of natural … that grab amino acids and stick them together to make small peptides. Those are fun, because the host organism can …
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