Search

Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore … of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based …

The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis … percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than … Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, …

The Sequencing Technologies Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing to enable biological discovery by the JGI and …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … can it actually turn over? ALISON NARAYAN: So that’s an excellent question. I think that we need enzymes with good … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community …

… other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from … Bowers RM, et al. (2017) Minimum information about a single amplified genome (MISAG) and a metagenome-assembled …